Review





Similar Products

rabbit anti p irf 3  (Proteintech)
96
Proteintech rabbit anti p irf 3
Rabbit Anti P Irf 3, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti p irf 3/product/Proteintech
Average 96 stars, based on 1 article reviews
rabbit anti p irf 3 - by Bioz Stars, 2026-02
96/100 stars
  Buy from Supplier
rabbit anti p irf3 ser396 polyclonal antibody  (Proteintech)
96
Proteintech rabbit anti p irf3 ser396 polyclonal antibody
Rabbit Anti P Irf3 Ser396 Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti p irf3 ser396 polyclonal antibody/product/Proteintech
Average 96 stars, based on 1 article reviews
rabbit anti p irf3 ser396 polyclonal antibody - by Bioz Stars, 2026-02
96/100 stars
  Buy from Supplier
anti p irf3  (Cell Signaling Technology Inc)
97
Cell Signaling Technology Inc anti p irf3
Anti P Irf3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti p irf3/product/Cell Signaling Technology Inc
Average 97 stars, based on 1 article reviews
anti p irf3 - by Bioz Stars, 2026-02
97/100 stars
  Buy from Supplier
p irf3  (Cell Signaling Technology Inc)
97
Cell Signaling Technology Inc p irf3
L. interrogans infection of macrophages induces a type I IFN response. (A-D) Quantification of TNF, IL-10, IL-6, and IFNβ by ELISA in culture supernatants of WT BMDMs infected with L. interrogans Fiocruz L1-130 (MOI 100) for 4, 6, and 8h. (E) Immunoblot for p-TBK1, total TBK1, <t>p-IRF3,</t> total IRF3 and β-actin in cell lysates of BMDMs infected with L. interrogans (MOI 100) for 2, 4, and 6h. Data are representative of three independent experiments. (F, G) Relative expression of Ifna and Ifnb transcript levels in BMDMs infected with L. interrogans at 4 and 6h post infection. (H) Relative expression of IFNB transcript levels in PMA-differentiated human THP-1 cells infected with L. interrogans at 4, 6, and 8h post infection. (A-D and F-H) Data are pooled from three independent experiments and expressed as the mean ± SEM.
P Irf3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/p irf3/product/Cell Signaling Technology Inc
Average 97 stars, based on 1 article reviews
p irf3 - by Bioz Stars, 2026-02
97/100 stars
  Buy from Supplier
rabbit anti p irf3 mab  (Cell Signaling Technology Inc)
97
Cell Signaling Technology Inc rabbit anti p irf3 mab
L. interrogans infection of macrophages induces a type I IFN response. (A-D) Quantification of TNF, IL-10, IL-6, and IFNβ by ELISA in culture supernatants of WT BMDMs infected with L. interrogans Fiocruz L1-130 (MOI 100) for 4, 6, and 8h. (E) Immunoblot for p-TBK1, total TBK1, <t>p-IRF3,</t> total IRF3 and β-actin in cell lysates of BMDMs infected with L. interrogans (MOI 100) for 2, 4, and 6h. Data are representative of three independent experiments. (F, G) Relative expression of Ifna and Ifnb transcript levels in BMDMs infected with L. interrogans at 4 and 6h post infection. (H) Relative expression of IFNB transcript levels in PMA-differentiated human THP-1 cells infected with L. interrogans at 4, 6, and 8h post infection. (A-D and F-H) Data are pooled from three independent experiments and expressed as the mean ± SEM.
Rabbit Anti P Irf3 Mab, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti p irf3 mab/product/Cell Signaling Technology Inc
Average 97 stars, based on 1 article reviews
rabbit anti p irf3 mab - by Bioz Stars, 2026-02
97/100 stars
  Buy from Supplier
p irf3 ser396  (Cell Signaling Technology Inc)
97
Cell Signaling Technology Inc p irf3 ser396
L. interrogans infection of macrophages induces a type I IFN response. (A-D) Quantification of TNF, IL-10, IL-6, and IFNβ by ELISA in culture supernatants of WT BMDMs infected with L. interrogans Fiocruz L1-130 (MOI 100) for 4, 6, and 8h. (E) Immunoblot for p-TBK1, total TBK1, <t>p-IRF3,</t> total IRF3 and β-actin in cell lysates of BMDMs infected with L. interrogans (MOI 100) for 2, 4, and 6h. Data are representative of three independent experiments. (F, G) Relative expression of Ifna and Ifnb transcript levels in BMDMs infected with L. interrogans at 4 and 6h post infection. (H) Relative expression of IFNB transcript levels in PMA-differentiated human THP-1 cells infected with L. interrogans at 4, 6, and 8h post infection. (A-D and F-H) Data are pooled from three independent experiments and expressed as the mean ± SEM.
P Irf3 Ser396, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/p irf3 ser396/product/Cell Signaling Technology Inc
Average 97 stars, based on 1 article reviews
p irf3 ser396 - by Bioz Stars, 2026-02
97/100 stars
  Buy from Supplier

Image Search Results


L. interrogans infection of macrophages induces a type I IFN response. (A-D) Quantification of TNF, IL-10, IL-6, and IFNβ by ELISA in culture supernatants of WT BMDMs infected with L. interrogans Fiocruz L1-130 (MOI 100) for 4, 6, and 8h. (E) Immunoblot for p-TBK1, total TBK1, p-IRF3, total IRF3 and β-actin in cell lysates of BMDMs infected with L. interrogans (MOI 100) for 2, 4, and 6h. Data are representative of three independent experiments. (F, G) Relative expression of Ifna and Ifnb transcript levels in BMDMs infected with L. interrogans at 4 and 6h post infection. (H) Relative expression of IFNB transcript levels in PMA-differentiated human THP-1 cells infected with L. interrogans at 4, 6, and 8h post infection. (A-D and F-H) Data are pooled from three independent experiments and expressed as the mean ± SEM.

Journal: bioRxiv

Article Title: cGAS-STING dependent type I IFN protects against Leptospira interrogans renal colonization in mice

doi: 10.1101/2025.06.02.657349

Figure Lengend Snippet: L. interrogans infection of macrophages induces a type I IFN response. (A-D) Quantification of TNF, IL-10, IL-6, and IFNβ by ELISA in culture supernatants of WT BMDMs infected with L. interrogans Fiocruz L1-130 (MOI 100) for 4, 6, and 8h. (E) Immunoblot for p-TBK1, total TBK1, p-IRF3, total IRF3 and β-actin in cell lysates of BMDMs infected with L. interrogans (MOI 100) for 2, 4, and 6h. Data are representative of three independent experiments. (F, G) Relative expression of Ifna and Ifnb transcript levels in BMDMs infected with L. interrogans at 4 and 6h post infection. (H) Relative expression of IFNB transcript levels in PMA-differentiated human THP-1 cells infected with L. interrogans at 4, 6, and 8h post infection. (A-D and F-H) Data are pooled from three independent experiments and expressed as the mean ± SEM.

Article Snippet: Primary antibodies from Cell signaling technologies (CST) were used as follows: TBK1 (CST #3504S), p-TBK1 (CST #5483S), IRF3 (CST #4302S), p-IRF3 (CST #4947S) and β-actin (CST #4970S).

Techniques: Infection, Enzyme-linked Immunosorbent Assay, Western Blot, Expressing